Loading a specific profile is quite straight forward and documented in this setting screen:
Source: http://forum.log4om.com/viewtopic.php?t=2641#p15009
Unanswered is howTo configure TQSL to sign the LOTW with the correct keys using TQSL.LOTW key, specify a station location for each key:
And choose the appropriate location in the LOTW Settings of Log4OM: