In theory, yes.
In practice, "probably not". In my experience, the front end on Baofengs is not very good. We have a UV-82, and it just did not work when we tried to use it for amateur satellites (AO-91, AO-92, etc). When we replaced it with a Yaesu FT-60R we were finally able to receive the "birds".
So while theoretically you should be able to receive LEO (low earth orbit) satellites (and the ISS), in reality your Baofeng is being overloaded by everything surrounding you. The same goes for cheap "RTL SDRs", which need some filtering to get a usable signal: Baofengs ARE SDRs, and cheap ones at that.
I haven't tried it, but maybe in the "middle of nowhere", far from broadcast stations, you would be able to receive the ISS. Or maybe if you use a suitable filter.
But if you want to experiment with ISS, amateur FM satellites, and NOAA APT (while they last), you should get a second hand "traditional" (analog, superheterodyne, etc) receiver, which will save you a lot of headache.